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Animal Frontiers Abstract - Feature Articles

Dairy cattle reproduction is a tightly regulated genetic process: Highlights on genes, pathways, and biological processes

 

This article in

  1. Vol. 5 No. 1, p. 32-41
     
    Published: January 6, 2015


    * Corresponding author(s): Laurent.schibler@unceia.fr
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doi:10.2527/af.2015-0006
  1. D. Valour*†,
  2. P. Michot,
  3. C. Eozenou*†,
  4. R. Lefebvre,
  5. A. Bonnet*,
  6. A. Capitan,
  7. S. Uzbekova,
  8. E. Sellem*†,
  9. C. Ponsart*†† and
  10. L. Schibler **
  1. * UNCEIA, 149 rue de Bercy, 75012 Paris, France
     INRA, UMR1198 Biologie du Développement et de la Reproduction, F-78350 Jouy en Josas, France
     INRA, UMR1313 Génétique Animale et Biologie Intégrative, F-78352 Jouy en Josas, France
     UMR INRA 85-CNRS 7247-Université de Tours, Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France
     †present address: ANSES, Laboratoire de Santé Animale, 14 rue Pierre et Marie Curie, 94701 Maisons-Alfort cedex

Abstract

  • Herd fertility is a key factor for the sustainability of cattle farming. However, declining fertility has become one of the main causes of culling and replacement of cows in developed countries.

  • Omics technologies have been successfully developed in cattle, refining our knowledge of molecular mechanisms governing cattle reproduction. However, most studies have failed to establish clear links between the genome and final phenotypes.

  • Further studies will be needed to integrate all Omics data and develop a systems biology modeling approach to tackle this complex biological function.

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Copyright © 2015. © 2015 Valour, Michot, Eozenou, Lefebvre, Bonnet, Capitan, Uzbekova, Sellem, Ponsart and Schibler